Alexander B
The circulating number of Endothelial Progenitor Cells (EPCs) decrease in patients with established heart failure (HF) depending the severity of the disease and may reflect poor prognosis. Developing type 2 diabetes mellitus (T2DM) associates with decreased number and weak function of EPCs that corresponds to impaired vascular repair and endothelial dysfunction. It is well known that T2DM is a risk factor of HF, but the role of EPC dysfunction in T2DM-induced HF is not fully investigated. The short communication is depicted a role of decreased circulating number and lowered function of EPCs in T2DM patients as a predictive biological marker of HF manifestation. It has been suggested that the potential use of EPCs as a novel personified indicator of cardiac dysfunction in diabetics is challenging and requires being under scrutinizes in future
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