Zeitschrift für diabetische Komplikationen und Medizin

Microvascular and Macrovascular Complications in type 1 Diabetes Following Islet Transplantation

Abstract

Dipakkumar Prajapati

High rates of microvascular and macrovascular disease-related morbidity and mortality are common in type 1 diabetes, which has a significant financial impact on society. The National Institute for Health and Care Excellence (NICE) recommends islet cell transplantation (ICT) as a treatment option for people with type 1 diabetes who suffer from debilitating hypoglycemia. This includes people who are in renal failure, where kidney transplantation may be necessary. Improving glycaemic control, reducing severe hypoglycemia, stabilizing glycaemic variability, and restoring awareness of hypoglycemia where it has been compromised are the primary goals of ICT.