Zeitschrift für diabetische Komplikationen und Medizin

Gastro Jejunal Inner Lumen Bypass Device Inhibits the Growth of Pigs

Abstract

Hidetoshi Matsunami, Noriko Sasaki, Tomomi Yoshikawa, Masao Takemura, Kazuhiro Watanabe, Sanae Shibata, Mifumi Kawabe, Tatsuya Matsubara, Yuki Murakami and Makoto Hayashi

The EndoBarrier has a weak point caused by a Teflon membrane, which completely inhibits the movement of water and food. We developed a new type of gastro jejunal inner lumen bypass device (GJB) using an artificial net that has a hole instead of a membrane. We inserted a net in the gastric antrum-duodenum–jejunum via open laparotomy. The growth of pigs with long nets was suppressed compared with the sham operation. However, there were no differences in blood biochemistry or anatomical findings at autopsy between the groups. As a result, GJB can control the growth of pigs without requiring dietary restriction.