Md. Harun-Or-Rashid*, Most. Nazmin Aktar, Md. Mizanur Rahman, Md. Mamunur Rashid Munna, Tarek Mohammad Nurul Islam, and Md. Touficul Hasan
Objective: Information on the clinical characteristics and studies of the infected patients have been required from December 2019, When throughout the China and globally spread it rapidly after arose it in Wuhan city first. Day by day this COVID-19 virus is becoming a Global concern of the public health. At present, more than 19,000 people have died globally infected by coronavirus, while more than 400,000 infections have been confirmed in more than fifteen dozens of countries, according to the World Health Organization.
Methods: We methodically searched and reviewed PubMed, Pub Centre, Web of Science, and Scopus with the following terms: “Middle East Respiratory Syndrome”, “MERSCoV” and “MERS”, Medline, Google scholar, Embase, Science Direct, Clinical Trials.gov, Newspapers, World Health Organization websites, and the Cochrane Central Database of Randomized Controlled Trials and treatment conducted prior to March 20, 2020.
Result: We reviewed published research papers on Coronavirus total 260 up to February 2020. We found that SARS-CoV was transmitted from animal to human. There are several drugs are prescribed for the infected patients of coronavirus such as Interferon Alfa-2B is an antiviral or antineoplastic drugs, Lopinavir plus ritonavir as antiviral therapy and also moxifloxacin to prevent secondary infection. In serious shortness of breathing and hypoxia methylprednisolone, antibody transmission and antiviral drugs are also prescribed for the infected patients. From the biopsy reports of lung in maximum papers showed alveolar damage and hyaline membrane formation.
Conclusion: Overall this review article will help to understand the transmission process, treatment, diagnosis and pathogenesis of the coronavirus.
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