Nemany A Hanafy, El-Kemary M and Leporatti S
The significant step in CaCO3 fabrication is to obtain homogenous population. There is a wide application in biomedical and industry market, since many reports have been investigated possible control of its diameter and shape during fabrication. Nowadays, CaCO3 template can be synthesised in diameter near or less than 120 nm. Control factors affected CaCO3 nucleation with integration of polymer inside were the main purpose in CaCO3 modification. In spite of great work that was done, designing of CaCO3 matrix as a way to be more attractive for hydrophobic cargo molecules could need a second eye for other investigation. The modification of CaCO3 matrix not only can provide mechanical support of all of CaCO3 architecture, or as a vehicle for hydrophobic molecules but also can be used as a smart vector for integration other drug delivery system such as liposome, micelles or even lipid nanoparticles.
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