Zeitschrift für chemische Wissenschaften

Extraction and Preservation Protocol of Anti-Cancer Agents from Marine World

Abstract

B Dhorajiya, M Malani, B Dholakiya

Marine source plays an important role in the form of pharmaceutical care and for the discovery of new molecular structures (i.e. targets). Marine organisms are a source of new therapeutics, especially for oncology, as a tremendous chemical diversity is found in marine bacteria, fungus, cyanobacteria, seaweeds, mangroves, microalgae and other halophytes. Several marine-derived compounds are currently extracted and synthesized by chemical processes for cancer treatment. By studying various papers related to marine source for new therapeutics for cancer treatment instead of other chemical enriched sources, the marine sources are largely unexplored for anti-cancer lead compounds. Hence this paper reviews results on the aspect with a view to provide basic information about the methods to produce extracts from marine organisms that are unique and different from that used by marine natural products chemists previously, yields both organic solvents and water soluble material for anti-cancer screening purpose. Chemists synthesize these compounds and their analogues in the laboratory for studying their activity towards various cancer cell lines.