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Predictors for the Time to Viral Load Suppression among HIV Positive Adults under HAART at Public Hospitals in Amhara Region: Application of Accelerated Failure Time

Abstract

Awoke Seyoum Tegegne

Background: Human immune deficiency virus weakens a person's defenses against infection and leading to acquired immune deficiency syndrome. The objective of this study was to identify predictors associated with time to viral load suppression among adult HIV positive patients under HAART in public Hospitals in Amhara Region.

Method: This study was conducted at public hospitals in Amhara region, Ethiopia using a Cross sectional study design. The source of data in this study was secondary source obtained from Amhara Public Health Institution. The data were collected by the health staff working at public hospitals in the region.

Result: Among the potential predictor variables under study, Patients aged between 25-34 years (AOR=0.694, 95% CI: (0.408-0.773), p-value=0.020), Tertiary Educated patients (AOR=0.860, 95% CI: 0.762-0.906, p-value=0.001), patients disclosed their disease status AOR=0.972, 95% CI: 0.701–0.997), p-value=0.014), patients with low baseline Viral load (AOR=0.949, 95% CI: 0.815–0.989), p-value=0.018), patients with high number of CD4 cells/mm3 (AOR=0.791, 95% CI: 0.819-0.890), p-value=0.021), good adherent patients (AOR=0.854, 95% CI;(0.746, 0.927), p-value=0.011) significantly associated with short time to viral load suppression. On the other hand, TB/HIV co-infected patients (AOR=1.317, 95% CI: 1.120, 1.436), p-value=0.015) and patients who used substance (AOR=1.241, 95% CI: (1.173, 1.383), p-value=0.026) significantly associated with longer time to viral load suppression.

Conclusion: The result in the current study revealed that significant predictor variables associated to time to viral load suppression were identified. Further studies should be done on HIV positive adult patients by considering other important independent variables not included in this study. Awareness should be created for patients to disclose their disease status and to be good adherent for their medication.

Haftungsausschluss: Dieser Abstract wurde mit Hilfe von Künstlicher Intelligenz übersetzt und wurde noch nicht überprüft oder verifiziert

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