Klinische Infektionskrankheiten: Open Access

Antimicrobial Prophylaxis in Surgical Procedures: Optimizing Strategies to Prevent Wound Infections

Abstract

Rashid Harunor

Antimicrobial prophylaxis refers to the administration of antibiotics or other antimicrobial agents to prevent infections in individuals at risk of
developing them. It is commonly used in various medical settings, including surgical procedures, dental work and certain medical conditions. The
primary goal of antimicrobial prophylaxis is to prevent the colonization and growth of bacteria or other microorganisms that can cause infection. In
surgical procedures, it aims to minimize the risk of Surgical Site Infections (SSIs), which can lead to complications, prolonged hospital stays and
increased healthcare costs. Antimicrobial prophylaxis involves the administration of antibiotics before surgery to prevent the growth of bacteria that
may be introduced during the procedure. The goal is to achieve adequate tissue concentrations of the antibiotic at the time of incision and during
the early postoperative period, which is when the risk of infection is highest.