Herz-Kreislauf-Erkrankungen und Diagnose

Uric Acid Levels Association with Different Risk Factors of Acute MI

Abstract

Abdul Ghaffar Memon, Iqbal Shah M, Santosh Kumar

Objective: To determine the association between serum uric acid (UA) levels and different risk factors ofacute myocardial infarction (AMI).

Methodology: Cross sectional study was containing on 120 patients with newly diagnosis of acute myocardial infarction and carried out in Department of Cardiologyof Liaquat university of Hospital Hyderabad with the duration of time from 15th June 2015 to 14th October 2015. All with age between 30 to 50 years either both gender were incorporated in the study. Serum uric acid was assessed through blood sample from Research and Diagnostic laboratory of Liaquat University of medical and health science. All the data was entered in the proforma.

Results: Mean age of the cases was 43.36 ± 6.11 years, male were found in the majority 66.67%. UA concentration was significantly higher in the male as compare to female P=value 0.02. According to the risk factors of the myocardial infarction high concentration of UA concentration was found in hypertensive 7.1 ± 1.5 mg/dland those who were noted with multiple risk factors 7.7 ± 1.8 mg/dl, following by Diabetes, obesity, dyslipidemia, smoking and Alcohol as: 6.1 ± 1.0 mg/dl, 6.9 ± 1.2 mg/dl, 6.7 ± 1.3 mg/dl and 7.0 ± 1.6 mg/dl respectively. While in the diabetes and family history cases uric acid was found with normal levels.

Conclusion: Elevated UA is highly associated with different risk factor of acute MI. From this inference uric acid level should be monitored in all risk factors especially in hypertensionand multiple risk factors.