Krebswissenschaft und -therapie

Patient with Chronic Myeloid Leukemia: A Case Study

Abstract

Muhammad Zeeshan Zafar

Introduction: Chronic myeloid leukemia abbreviated as CML is a type of myeloproliferative disease characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood. It is a clonal bone marrow stem cell disorder in which a proliferation of mature granulocytes and their precursor is found.

Case presentation: We report the case of 58-year-old Asian lady experiencing generalized body weakness, pallor, left upper abdominal pain and sudden weight loss of 5 kg within three weeks and a high blood pressure of 190/110. She has initially diagnosed splenomegaly and a mild heart attack. Various laboratory tests including complete blood count were conducted and the test results revealed a myeloproliferative disorder. The oncologist suggested bone marrow aspiration that led to a diagnosis of chronic myeloid leukemia. The disease was thought treated at an early stage but the case became complicated by previous untreated pathological conditions.

Conclusion: Not all cases of CML are complicated in such a critical manner. Our report emphasizes on the fact of the need of good clinical evaluation by a qualified therapist and use of appropriate investigative studies is mandatory in order to secure patient from such a critical health condition.