Zeitschrift für mikrobielle Pathogenese

Novel Approaches to Combat Biofilm Formation in Staphylococcus aureus

Abstract

Ernst Franz

Biofilm formation by Staphylococcus aureus poses a significant challenge in clinical settings, contributing to persistent infections and antibiotic resistance. This review explores innovative strategies to prevent and disrupt biofilms, including the use of antimicrobial peptides, quorum sensing inhibitors, and novel drug delivery systems. We also examine the potential of bacteriophage therapy and the role of nanotechnology in enhancing treatment efficacy. By understanding and targeting the unique characteristics of S. aureus biofilms, these novel approaches hold promise for improving patient outcomes and reducing healthcare costs associated with chronic infections.