Krebswissenschaft und -therapie

Initial Diagnosis of Psoriasis and Final Diagnosis of Cutaneous T-Cell Lymphoma/Sézary Syndrome

Abstract

Estefania G. Piedrahita, Maria A. G. Abad, Ángela M. L. García and José D. S. Ramírez

Cutaneous T-cell lymphomas are part of non-Hodgkin lymphomas that mainly affects the skin but can compromise blood, lymph nodes and other
internal organs in patients with advanced disease. There are many types of cutaneous T-cell lymphoma. The two main subtypes are mycosis
fungoides (MF) and Sézary syndrome (SS). The diagnosis of the latter is a challenge due to the clinical and some histological findings, which
makes them similar to benign dermatoses. The clinical case of a patient with an initial diagnosis of erythroderma associated with psoriasis with
joint involvement is presented, then the etiology is re-evaluated and an extra cutaneous nodal T lymphoma with bone marrow involvement (Sézary
syndrome) is confirmed.