Zeitschrift für Molekulare Histologie und Medizinische Physiologie

Histology of Meissnerâ??s Corpuscles

Abstract

Vikrant Singh

Professor Georg Meissner and Professor Rudolf Wagner originally characterized Meissner corpuscles in 1852. They are also known as Wagner-Meissner corpuscles or tactile corpuscles. These unique encapsulated nerve terminals are found in the dermal papillae of glabrous skin and convey delicate touch and low-frequency vibration sensations to the central nervous system (CNS). Meissner corpuscles are important for somatosensory acuity, particularly in the digital extremities and palmar skin, and have clinical implications for peripheral and diabetic neuropathy, as well as age-related degradation of dermatological tactile sensibility