Zeitschrift für klinische Krebsstudien

Advanced DNA-Biomacromolecule Sensor: Enhancing Sensitivity in Clinical Cancer Sample Detection

Abstract

John Paulisen

An ultrasensitive DNA-biomacromolecule system or technology has the capability to detect and analyze DNA molecules with exceptional sensitivity. DNA, serving as the fundamental genetic material in living organisms, holds critical significance in numerous biological processes and finds extensive applications in diagnostics and research. Ultrasensitive DNA-biomacromolecule technologies are specifically engineered to identify and quantify minute amounts of DNA molecules within a given sample. Employing diverse detection methodologies such as fluorescence, electrochemical sensing, nanopore sequencing, or amplification techniques like polymerase chain reaction, these technologies enable scientists to achieve remarkably precise and sensitive detection of DNA molecules, even when present in exceedingly low concentrations.