Herz-Kreislauf-Erkrankungen und Diagnose

A Study of Measurement of ASCVD Risk Parameters in Patients with Clinical Atherosclerotic Cardiovascular Disease

Abstract

Suresh V Patted, Sanjay C Porwal, Sameer Ambar, Prasad MR, Shekhar Bhise, Vishwanath Hesarur, Vaibhav Patil and Suhasini Atharga

Objectives: To measure Atherosclerotic Cardiovascular Disease (ASCVD) risks and parameters in patients with clinical ASCVD.

Materials and methods: This retrospective study was conducted in Cardiology Department of KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, a tertiary care center situated in North Karnataka, Belagavi, India. Data was collected from January 2018 to December 2018. A total 952 patients with clinical ASCVD aged >40 years who were on statin therapy were included in the study. The records of patients with ASCVD were evaluated for risk parameters based on ACC AHA cholesterol guidelines 2018.

Results: Out of 952 patients, consisting of 77% of the patients were males and 23% were females. The mean age was 62.45 ± 8.18 years. Most of the patients (43.7%) were aged between 61 to 70 years. Overall 51.37% of the patients had positive history of hypertensive treatment, followed by history of diabetes mellitus, prior revascularization, smoking, Congestive cardiac failure (CCF) and chronic kidney disease (CKD). None of the patient had heterozygous familial hypercholesterolemia. With regard to lipid abnormalities, majority of the patients (60.61%) had low high-density lipoprotein (HDL) followed by hypertriglyceridemia, elevated low-density lipoprotein (LDL) and hypercholesterolemia.

Conclusion: Most common risk factor for ASCVD is hypertension followed by diabetes, dyslipidemia and smoking. With incidence being higher in very high clinical ASCD compared to stable ASCVD.