Krebswissenschaft und -therapie

A Rare Presentation of Zosteriform Pattern of Cutaneous Metastases from Lung Cancer: A Case Report and Literature Review on Cutaneous Metastases in Non-Small Cell Lung Cancer

Abstract

Matthew Lee, Shikha Sheth, Syed Ahmad, Qing Chang and Nagashree Seetharamu

Background: Lung cancer typically metastasizes to the brain, bone, liver and adrenal glands but can rarely metastasize to the skin. It has been reported in only 1-12% of lung cancer cases and can be an initial finding in newly diagnosed lung cancer patients. These rare findings can be the first indication of a quiescent lung cancer.

Case presentation: This is a case report on a former smoker that initially presented with skin metastases in a zosteriform pattern that was found to be from primary lung adenocarcinoma. He first developed swelling in his left upper extremity and then a rash that was later became vesicular and in ad dermatomal pattern. A subsequent biopsy later revealed this to be from primary adenocarcinoma of the lung.

Conclusion: This case highlights the importance of recognizing skin manifestations in high risk patients with smoking history of lung cancer diagnoses and the need for further research on the mechanism of this etiology and treatment options.